Alkylation reactions replace active hydrogens by an aliphatic or aliphatic-aromatic (benzyl) group. The principal use of this mode of derivation is to improve upon the chromatography of compounds such as free organic acids. Alkylation reactions can form ethers, thioethers, thioesters, n-alkylamines, amides and sulfonamides. These derivatives possess excellent stability and can be stored for extended periods of time.
TMPAH
0.2M Trimethylanilium hydroxide in Methanol
Part Number
STMPAH-0-1
STMPAH-0-10
STMPAH-0-25
STMPAH-0-100
Quantity
1 gm vial
10 gm vial
25 gm vial
100 gm vial
Units per pack
10
1
1
1
- Used for the methylation of barbiturates, sedatives, xanthines, and alkaloids by GC.
- The derivatization of these compounds often can be done in the injector of the GC.
4 CB
4-Carbethoxyhexafluorobutyrl Chloride
Part Number
S4CB-0-1
S4CB-0-10
S4CB-0-25
Quantity
1 gm vial
10 gm vial
25 gm vial
Units per pack
10
1
1
- Peptides + Propionic anhydride converts N-termini and Lysines to propyl amides. This results in a decrease in net charge of the peptides and increased hydrophobicity.