The addition of solvents to derivatization reactions is a critical step in the reaction process. Solvents are used to solubilize the analyte and promote reaction conditions that will improve the yield of the reaction.
Listed below are the most common solvents used in this process.
Specialized Reagents
PFPOH
Pentafluoropropanol
Part Number
SPFPOH-0-1
SPFPOH-0-10
SPFPOH-0-25
SPFPOH-0-100
Quantity
1 gm vial
10 gm vial
25 gm vial
100 gm vial
Units per pack
10
1
1
1
- Used in combination with the acid anhydrides to add more fluorine atoms to the parent molecule.
- This reaction is especially used for carboxylic acids.
- The addition of fluorine atoms into the molecule greatly adds to the sensitivity of certain detectors (i. e. ECD, MS).
HFIP
Hexafluoro-2-propanol
Part Number
SHFIP-0-1
SHFIP-0-10
SHFIP-0-25
SHFIP-0-100
Quantity
1 gm vial
10 gm vial
25 gm vial
100 gm vial
Units per pack
10
1
1
1
- Used in combination with the acid anhydrides to add more fluorine atoms to the parent molecule.
- This reaction is especially used for carboxylic acids.
- The addition of fluorine atoms into the molecule greatly adds to the sensitivity of certain detectors (i. e. ECD, MS).
Solvents for Derivatizing Reagents
Solvent
Acetonitrile (ACN)
Dimethylformamide (DMF)
Dimethyl Sulfoxide (DMSO)
Pyridine
Tetrahydrofuran (THF)
Part Number
SACN-0-50
SDMF-0-50
SDMS0-0-50
SPYR-0-50
STHF-0-50
Size
50 mL vial
50 mL vial
50 mL vial
50 mL vial
50 mL vial
Units
1
1
1
1
1