CLEAN SCREEN® - RSV

Reduced Solvent Volume Extraction Columns

 

Reduced Solvent Volume extraction columns are micro bed packed columns which offer the advantages of disc technology yet maintain the proven track record of our conventional SPE columns. Reduced Solvent Volume columns use 75% less solvent than traditional packed columns. Less solvent means faster extractions, higher throughput and less waste disposal, which translates into significant savings in both time and money. Results demonstrate that therapeutic and abused drugs in urine and blood matrices can be extracted with cleanliness, high recoveries and consistent reproducibility by using the Reduced Solvent Volume extraction column.

 

RSV columns are available in 1 mL, 3 mL and 10 mL configurations. These columns can be used with vacuum manifolds or positive pressure, as well as conventional automated extraction equipment.

 

 

Advantages  of CLEAN SCREEN® RSV:

  • 75% Reduction in total liquid volumes
  • Lower cost per extraction
  • Faster extraction times
  • Less disposal cost
  • Increased automated throughput
  • 50% Reduction in eluate volume
  • Faster dry down times
  • Reduced exposure to organic solvents
  • Superior flow characteristics
  • Less flow restriction from matrix proteins or particulates
  • More reliable for automated processing
  • High capacity
  • Greater linear range

 

Absolute Recovery

THC-COOH Standards (ng/ml)

in spiked urine

Capacity

91% (n=4) for 1000 ng/ml

90% (n=2) for 3000 ng/ml

91% (n=4) for 4000 ng/ml

 

 

No Analyte breakthrough at 1000 ng/ml and less than 0.2% analyte breakthrough at 3000 and 4000 ng/ml levels.

 

Concentration (ng/ml)

Analyte

Recovery

 

Linear Ranges Exhibiting

Greater than

85% Recoveries in Urine

 

===  Highest Concentrations Tested

===  Lowest Concentrations Tested

 

Solvent Reduction

Analyte

Solvent Usage

Reduced Solvent

Volume

SPE columns

Solvent Usage

Traditional Packed

columns

% Solvent

Reduction

Barbiturates

Benzoylecgonine

THC-COOH

Phencyclidine

4.25 mL

4.65 mL

4.85 mL

5.15 mL

18 mL

19 mL

16.4 mL

19 mL

76%

76%

73%

70%

 

Copolymeric Extraction for All Drug Classes

Part Number

With

Clean-Thru® Tips

CSDAUA51

CSDAUA83

ZSDAUA08Z

Part Number

Without

Clean-Thru® Tips

CCDAUA51

CCDAUA83

ZCDAUA08Z

Sorbent Amount/

Tube Volume

50mg/1mL

80mg/3mL

80mg/10mL

Unit per

Pack

100

50

50

CLEAN SCREEN® DAU

Column is copolymerized on a rigid, purified silica gel support. The two functional groups include a reverse phase, and an ion exchanger, benzenesulfonic acid. This column is commonly used for analyzing a wide range of drugs of abuse, including acidic, basic and neutral drugs.

 

Specifically for THC & THCA Extraction

Part Number

With

Clean-Thru® Tips

CSTHCA51

CSTHCA83

ZSTHCA08Z

Part Number

Without

Clean-Thru® Tips

CCTHCA51

CCTHCA83

ZCTHCA08Z

Sorbent Amount/

Tube Volume

50mg/1mL

80mg/3mL

80mg/10mL

Unit per

Pack

100

50

50

CLEAN SCREEN® THC

Column is copolymerized on a rigid, purified silica gel support. The two functional groups include a reverse phase, and an ion exchanger, quaternary amine. This column is commonly used for analyzing THC and its metabolites.

 

CLEAN-UP® - RSV

Reduced Solvent Volume Extraction Columns

C18, Octadecyl Tri-Functional

Part Number

Endcapped

CEC18A051

CEC18A083

CEC18A08Z

Part Number

Unendcapped

CUC18A051

CUC18A083

CUC18A08Z

Sorbent Amount/

Tube Volume

50mg/1mL

80mg/3mL

80mg/10mL

Unit per

Pack

100

50

50

% Organic Loading: 21.70

Application:

Removes hydrophobic impurities, de-salting and purification of hydrophobic compounds.